Current ACRC Studies
ASTHMA AND ACID REFLUX DISEASE: TREATING ONE CONDITION CAN RELIEVE THE OTHER
SARA: Study of Acid Reflux and Asthma
Funded by the National Institute of Health’s National, Heart, Lung and Blood Institute
Acid reflux disease, also known as gastro-esophageal reflux disease or GERD, is frequent among people with poorly controlled asthma. It often occurs with no symptoms and can induce constriction of the airways. Poorly controlled asthma patients are frequently treated for GERD with drugs that suppress gastric acid, but this approach is expensive and its benefit has not been established. This clinical trial is testing the hypothesis that treating GERD with a class of drugs called proton pump inhibitors will reduce the frequency of exacerbations (worsening of the problem) in people with inadequately controlled asthma. Four hundred people between the ages of 18 and 60 who have asthma that is not well controlled with inhaled steroids are being studied, and are randomly assigned to treatment with either a proton pump inhibitor or a placebo. The results will point the way to more effective methods to control acid reflux and prevent it from contributing to asthma.
Centers are currently recruiting for this trial. Click here for more information.
CHILDHOOD ASTHMA AND ACID REFLUX DISEASE: TREATING ONE CONDITION CAN RELIEVE THE OTHER
SARCA: Study of Acid Reflux and Childhood Asthma
Funded by the National Institute of Health’s National, Heart, Lung and Blood Institute
Acid reflux disease, also known as gastro-esophageal reflux disease or GERD, is frequent among people with poorly controlled asthma. It often occurs with no symptoms and can induce constriction of the airways. Poorly controlled asthma patients are frequently treated for GERD with drugs that suppress gastric acid, but this approach is expensive and its benefit has not been established. This clinical trial is testing the hypothesis that children with symptomatic asthma have improved asthma control when treated for gastroesophageal reflux disease (GERD) with a class of drugs called proton pump inhibitors. Three hundred children between the ages of 6 and 17 who have asthma that is not well controlled with inhaled steroids are being studied, and are randomly assigned to treatment with either a proton pump inhibitor or a placebo. The results will point the way to more effective methods to control acid reflux and prevent it from contributing to asthma.
Centers are currently recruiting for this trial1. Click here for more information.
1 The center at Louisiana State University is not participating in the SARCA trial
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